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The Learn2Reg 2021 MICCAI Grand Challenge (PIMed Team)

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Biomedical Image Registration, Domain Generalisation and Out-of-Distribution Analysis (MICCAI 2021)

Abstract

This paper summarizes our approaches and results for the three tasks of the Learn2Reg 2021 MICCAI Grand Challenge focused on the registration of: (1) intra-patient abdominal CT and MR images, (2) intra-patient expiration and inspiration lung CT scans, and (3) inter-patient brain MR images. These registration tasks have multiple challenges including dealing with multi-modal scans, estimating large deformations, lack of training data, and missing data. For Task 1, we first segmented four organs in both CT and MRI and, second, used them in a two-stage deformable registration pipeline. Our approach has achieved a Dice coefficient of 0.71. For Task 2, we handled missing data in the expiration CT by using a pairwise geodesic density registration algorithm that excludes data outside the lungs. Our approach has achieved a target registration error of 2.3 mm. For Task 3, we modified the VoxelMorph architecture to give more degrees of freedom to the registration model and used it to register brain MRI across patients. Our approach has achieved a Dice coefficient of 0.78. Overall, our team has won second place out of 35 submissions from 15 teams.

W. Shao and S. Vesal—Equal contribution as first authors.

G. Sonn and M. Rusu—Equal contribution as senior authors.

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References

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Acknowledgments

This work was supported by the Department of Radiology and the Department of Urology at Stanford University.

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Correspondence to Wei Shao , Sulaiman Vesal or Mirabela Rusu .

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Shao, W. et al. (2022). The Learn2Reg 2021 MICCAI Grand Challenge (PIMed Team). In: Aubreville, M., Zimmerer, D., Heinrich, M. (eds) Biomedical Image Registration, Domain Generalisation and Out-of-Distribution Analysis. MICCAI 2021. Lecture Notes in Computer Science(), vol 13166. Springer, Cham. https://doi.org/10.1007/978-3-030-97281-3_24

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  • DOI: https://doi.org/10.1007/978-3-030-97281-3_24

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-97280-6

  • Online ISBN: 978-3-030-97281-3

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