I'm not sure if I'm interpreting the rules incorrectly or if there's a bug.
I kept rolling until there were only two dice in my Ready Pool. I eventually rolled a 1 on my Stress Die, which reduced my Ready Pool to one die - just the Stress Die. But then when I went to roll again I was able to select all the check boxes for all of the other dice - they were no longer greyed out. That seemed odd because I had not Rested yet to replenish my dice pool.
Maybe I'm misunderstanding some element of the exhaustion/replenishment rules.