Parameter inference for stochastic single-cell dynamics from lineage tree data

I Kuzmanovska, A Milias-Argeitis, J Mikelson… - BMC systems …, 2017 - Springer
Background With the advance of experimental techniques such as time-lapse fluorescence
microscopy, the availability of single-cell trajectory data has vastly increased, and so has the
demand for computational methods suitable for parameter inference with this type of data.
Most of currently available methods treat single-cell trajectories independently, ignoring the
mother-daughter relationships and the information provided by the population structure.
However, this information is essential if a process of interest happens at cell division, or if it …

[PDF][PDF] Parameter inference for stochastic single-cell dynamics from lineage tree data Kuzmanovska, Irena; Milias Argeitis, Andreas; Mikelson, Jan; Zechner, Christoph

M Khammash - 2017 - core.ac.uk
Background: With the advance of experimental techniques such as time-lapse fluorescence
microscopy, the availability of single-cell trajectory data has vastly increased, and so has the
demand for computational methods suitable for parameter inference with this type of data.
Most of currently available methods treat single-cell trajectories independently, ignoring the
mother-daughter relationships and the information provided by the population structure.
However, this information is essential if a process of interest happens at cell division, or if it …
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