Modeling protein loops with knowledge-based prediction of sequence-structure alignment
… a knowledge-based loop prediction method that … loop libraries. The method first predicts
local structural fragments of a query loop sequence and then structurally aligns the predicted …
local structural fragments of a query loop sequence and then structurally aligns the predicted …
Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction
C Marks, J Nowak, S Klostermann, G Georges… - …, 2017 - academic.oup.com
… From the results presented in this paper, we believe that in a real loop modelling situation
a knowledge-based method such as FREAD should be tried first (since such methods are …
a knowledge-based method such as FREAD should be tried first (since such methods are …
Knowledge-based prediction of protein structures and the design of novel molecules
… The database for such prediction of conformation in loops is now being constructed.
Sibanda and Thornton" and MilnerWhite and Poet" have detailed the conformations of 8-hairpin …
Sibanda and Thornton" and MilnerWhite and Poet" have detailed the conformations of 8-hairpin …
Protein Structure Prediction: Knowledge-based Approaches for Loop Prediction and Model Quality Assessment
P Benkert - 2007 - kups.ub.uni-koeln.de
… other knowledge-based loop prediction … loop including side chains with its structural
environment. On a large test set of over 200 loops, the loop prediction method is able to model loops …
environment. On a large test set of over 200 loops, the loop prediction method is able to model loops …
Knode-mpc: A knowledge-based data-driven predictive control framework for aerial robots
… However, it is unclear whether such hybrid models could improve the closed-loop … only
provides better predictions of future states, but also improves the closed-loop performance in both …
provides better predictions of future states, but also improves the closed-loop performance in both …
KORP: knowledge-based 6D potential for fast protein and loop modeling
JR López-Blanco, P Chacón - Bioinformatics, 2019 - academic.oup.com
… We have developed KORP, a knowledge-based pairwise potential for proteins that depends
… in recent critical assessment of protein structure prediction and loop-modeling benchmarks. …
… in recent critical assessment of protein structure prediction and loop-modeling benchmarks. …
Knowledge based prediction of ligand binding modes and rational inhibitor design for kinase drug discovery
AK Ghose, T Herbertz, DA Pippin… - Journal of medicinal …, 2008 - ACS Publications
… is to employ a knowledge based approach, utilizing … loop, known as the glycine-rich loop
for its highly conserved GXGXXG motif; this loop is alternatively designated the G-loop or P-loop…
for its highly conserved GXGXXG motif; this loop is alternatively designated the G-loop or P-loop…
Antibody structure determination using a combination of homology modeling, energy‐based refinement, and loop prediction
… -H3 CDR loops range from 0.61 Å to 1.05 Å, and the H3 loop average RMSD is 2.91 Å using
our knowledge-based loop prediction approach. The ab initio H3 loop predictions yield an …
our knowledge-based loop prediction approach. The ab initio H3 loop predictions yield an …
Improving loop modeling of the antibody complementarity-determining region 3 using knowledge-based restraints
… structural predictions are a more … loops, which had made it possible to homology model
much of the functional surface of the antibody (the “paratope”) using Rosetta, we can now predict …
much of the functional surface of the antibody (the “paratope”) using Rosetta, we can now predict …
Fuzzy knowledge-based prediction through weighted rule interpolation
… FOR PREDICTION A fuzzy sparse knowledge-based inference mechanism for prediction is
… Lines 9–12 form a for loop with each step in the loop (ie, lines 10 and 11) taking a unit time …
… Lines 9–12 form a for loop with each step in the loop (ie, lines 10 and 11) taking a unit time …
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