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Task-Adapted Single-Finger Explorations of Complex Objects
The perception of material/object properties plays a fundamental role in our daily lives. Previous research has shown that individuals use distinct...
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Sororin is an evolutionary conserved antagonist of WAPL
Cohesin mediates sister chromatid cohesion to enable chromosome segregation and DNA damage repair. To perform these functions, cohesin needs to be...
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Active afforestation of drained peatlands is not a viable option under the EU Nature Restoration Law
The EU Nature Restoration Law (NRL) is critical for the restoration of degraded ecosystems and active afforestation of degraded peatlands has been...
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Dopamine regulates decision thresholds in human reinforcement learning in males
Dopamine fundamentally contributes to reinforcement learning, but recent accounts also suggest a contribution to specific action selection mechanisms...
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Single cohesin molecules generate force by two distinct mechanisms
Spatial organization of DNA is facilitated by cohesin protein complexes that move on DNA and extrude DNA loops. How cohesin works mechanistically as...
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SensEURCity: A multi-city air quality dataset collected for 2020/2021 using open low-cost sensor systems
Low-cost air quality sensor systems can be deployed at high density, making them a significant candidate of complementary tools for improved air...
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Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments
DNA loop extrusion by structural-maintenance-of-chromosome (SMC) complexes has emerged as a primary organizing principle for chromosomes. The...
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Igh and Igk loci use different folding principles for V gene recombination due to distinct chromosomal architectures of pro-B and pre-B cells
Extended loop extrusion across the immunoglobulin heavy-chain ( Igh ) locus facilitates V H -DJ H recombination following downregulation of the...
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CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion
In eukaryotes, genomic DNA is extruded into loops by cohesin
1 . By restraining this process, the DNA-binding protein CCCTC-binding factor (CTCF)...
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Proximale Femurfraktur bei knöcherner Ankylose des Hüftgelenks
A 78-year-old female patient sustained a left-sided proximal femoral fracture due to a fall. Since childhood the patient had suffered from ankylosis...
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Large-Scale Web Scraping for Problem Gambling Research: A Case Study of COVID-19 Lockdown Effects in Germany
The COVID-19 pandemic and the measures to prevent its spread have had a negative impact on substance use behaviour. It is likely that social...
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Soft Robot Assistance for Tumor Biopsy and Ablation in Magnetic Resonance Imaging
This work presents a soft robotic system that supports interventionalists in tumor diagnostics through biopsy and ablation in the magnetic resonance...
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Auto(mated)nomous Assembly
The paper presents research on a hierarchical, computational design approach for the aggregation of dry-joint, interlocking building blocks and their...
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Stellung der Unfallchirurgie in der Notfallmedizin
BackgroundThe decision of the Federal Joint Committee has resulted in the further development of in-hospital emergency medicine through the...
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Parameter and Model Recovery of Reinforcement Learning Models for Restless Bandit Problems
Multi-armed restless bandit tasks are regularly applied in psychology and cognitive neuroscience to assess exploration and exploitation behavior in...
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MCM complexes are barriers that restrict cohesin-mediated loop extrusion
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs)
1 –3 , which contribute to transcription, recombination and...
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PAC-Bayesian lifelong learning for multi-armed bandits
We present a PAC-Bayesian analysis of lifelong learning. In the lifelong learning problem, a sequence of learning tasks is observed one-at-a-time,...
