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Integrating microbial GWAS and single-cell transcriptomics reveals associations between host cell populations and the gut microbiome
Microbial genome-wide association studies (GWAS) have uncovered numerous host genetic variants associated with gut microbiota. However, links between...
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Performance evaluation of spaceborne combined IPDA LIDAR and DIAL for simultaneous measurement of methane column concentrations and water vapor density profile
Methane (CH 4 ) is one of the most important greenhouse gases, and its impact on climate change is gradually increasing owing to increased emissions....
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Sensing Compound Substructures Combined with Molecular Fingerprinting to Predict Drug-Target Interactions
Identification of drug-target interactions (DTIs) is critical for drug discovery and drug repositioning. However, most DTI methods that extract...
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Classification of cracking potential for clayey soils based on cyclic wet-dry tests
The substantial development of desiccation cracks profoundly impacts the mechanical and hydraulic properties of clayey soils, potentially leading to...
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Ochratoxin A-induced mitochondrial pathway apoptosis and ferroptosis by promoting glycolysis
Ochratoxin A (OTA), a toxic secondary metabolite recognized for its harmful effects on the kidneys, and it is commonly present in various foods and...
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Impaired emotional response inhibition among adolescents with bipolar depression: evidence from event-related potentials and behavioral performance
BackgroundImpaired inhibition of inappropriate responses in the emotional context is a core feature in patients with bipolar disorder. However, there...
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Personalized prediction of esophageal cancer risk based on virtually generated alcohol data
BackgroundEsophageal cancer (EC) presents a significant public health challenge globally, particularly in regions with high alcohol consumption. Its...
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Ketorolac in the perioperative management of acute type A aortic dissection: a randomized double-blind placebo-controlled trial
BackgroundAcute Type A Aortic Dissection (aTAAD) is a severe and life-threatening condition. While animal studies have suggested that ketorolac could...
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Research advances and future perspectives of zinc-based biomaterials for additive manufacturing
AbstractAdditive manufacturing (AM) of zinc-based biodegradable materials is a hot research topic, especially for bone-scaffold applications, because...
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Salvia japonica essential oil as biocontrol agent: suppressing Fusarium oxysporum in Pinus sylversteis Var. Mongolica seedling blight
Salvia japonica essential oil (SJEO) is a natural active substance that has been widely used in medicine and food preservation. However, the...
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Polarity modulation in compositionally tunable Bi2O2Se thin films
Two-dimensional (2D) materials have emerged as one of most promising candidates to meet the demands of beyond-silicon technology. Among 2D...
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Generation and manipulation of light-induced orbital transport in Co/Zr/Al2O3 heterostructure probed with ultrafast terahertz emission
The utilization of terahertz (THz) emission spectroscopy in femtosecond photoexcited spintronic heterostructures has emerged as a versatile tool for...
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Effect of heavy metal copper on the physiological characteristics of Ulva lactuca at different temperatures
Copper (Cu) is an essential element for macroalgae and has been extensively studied, but the interactive effects of temperature and Cu on these...
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Mott insulating phase and coherent-incoherent crossover across magnetic phase transition in 2D antiferromagnetic CrSBr
In two-dimensional van der Waals magnetic materials, the interplay between magnetism and electron correlation can give rise to new ground states and...
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OSGEP, A Negative Ferroptotic Regulator, Alleviates Cerebral Ischemia–Reperfusion Injury Through Modulating m6A Methylation of GPX4 mRNA
Cerebral ischemia–reperfusion injury (CIRI) is a devastating condition that triggers neuronal death and cerebral infarction. O-sialoglycoprotein...
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Apoptotic cell-derived extracellular vesicles-MTA1 confer radioresistance in cervical cancer by inducing cellular dormancy
BackgroundRadioresistance presents a major challenge in the treatment of cervical cancer (CC). Apoptotic tumor cells can create an “onco-regenerative...
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Can we distinguish between adiabatic and isocurvature fluctuations with pulsar timing arrays?
Understanding the nature of primordial fluctuations is pivotal to unraveling the Universe’s early evolution. While these fluctuations are observed to...
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Is PSR J0514–4002E in a PBH-NS binary?
Recent pulsar timing observations using MeerKAT of the eccentric binary millisecond pulsar, PSR J0514–4002E, have unveiled a companion with a mass in...
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High-performance solution-processed OLEDs utilizing a nonplanar terdentate chloroplatinum emitter
Platinum complexes are one of the most promising emitters for organic light-emitting diodes (OLEDs) and they have been studied for decades. However,...