Abstract
Deep learning has demonstrated great success in various computer vision tasks. However, tracking the lumbar spine by digitalized video fluoroscopic imaging (DVFI), which can quantitatively analyze the motion mode of the spine to diagnose lumbar instability, has not yet been well developed due to the lack of steady and robust tracking method. The aim of this work is to automatically track lumbar vertebras with rotated bounding boxes in DVFI sequences. Instead of distinguishing vertebras using annotated lumbar images or sequences, we train a full-convolutional siamese neural network offline to learn generic image features with transfer learning. The siamese network is trained to learn a similarity function that compares the labeled target from the initial frame with the candidate patches from the current frame. The similarity function returns a high score if the two images depict the same object. Once learned, the similarity function is used to track a previously unseen object without any adapting online. Our tracker is performed by evaluating the candidate rotated patches sampled around the previous target’s position and presents rotated bounding boxes to locate the lumbar spine from L1 to L4. Results indicate that the proposed tracking method can track the lumbar vertebra steadily and robustly. The study demonstrates that the lumbar tracker based on siamese convolutional network can be trained successfully without annotated lumbar sequences.





Similar content being viewed by others
References
Landi A, Gregori F, Marotta N, Donnarumma P, Delfini R: Hidden spondylolisthesis: unrecognized cause of low back pain? Prospective study about the use of dynamic projections in standing and recumbent position for the individuation of lumbar instability. Neuroradiology 57(6):583–588, 2015
Ahn K, Jhun HJ: New physical examination tests for lumbar spondylolisthesis and instability: low midline sill sign and interspinous gap change during lumbar flexion-extension motion. BMC musculoskeletal disorders 16(1):97–103, 2015
Patriarca L, Letteriello M, Di Cesare E, Barile A, Gallucci M, Splendiani A: Does evaluator experience have an impact on the diagnosis of lumbar spine instability in dynamic MRI Interobserver agreement study. Neuroradiol 28(3):341–346, 2015
Sui F, Zhang D, Lam SCB, Zhao L, Wang D, Bi Z, Hu Y: Auto-tracking system for human lumbar motion analysis. Journal of X-ray Science and Technology 19(2):205–218, 2011
Clarke MJ, Zadnik PL, Groves ML, Sciubba DM, Witham TF, Bydon A, Wolinsky JP: Fusion following lateral mass reconstruction in the cervical spine. Journal of Neurosurgery: Spine 22(2):139–150, 2015
Kettler A, Rohlmann F, Ring C, Mack C, Wilke HJ: Do early stages of lumbar intervertebral disc degeneration really cause instability? Evaluation of an in vitro database. European Spine Journal 20(4):578–584, 2011
Miyasaka K, Ohmori K, Suzuki K, Inoue H: Radiographic analysis of lumbar motion in relation to lumbosacral stability: investigation of moderate and maximum motion. SPINE 25(6):732–737, 2000
Bertinetto L, Valmadre J, Henriques J F, et al. Fully-Convolutional Siamese Networks for Object Tracking. European Conference on Computer Vision – ECCV2016, 2016:850–865.
Kumar VP, Thomas T: Automatic estimation of orientation and position of spine in digitized X-rays using mathematical morphology. Journal of Digital Imaging 18(3):234–241, 2005
Benjelloun M, Mahmoudi S: Spine localization in X-ray images using interest point detection. Journal of Digital Imaging 22(3):309–318, 2009
Liu Y, Sui X, Sun Y, Liu C, Hu Y: Siamese convolutional networks for tracking the spine motion. In Applications of Digital Image Processing XL. International Society for Optics and Photonics 10396(103961Y), 2017
Zhou Y, Liu Y, Chen Q, Gu G, and Sui X. Automatic Lumbar MRI Detection and Identification Based on Deep Learning. Journal of digital imaging, 32:513, 2019, 520
SMMR AA, Knapp K, Slabaugh G: Fully automatic cervical vertebrae segmentation framework for X-ray images. Computer Methods & Programs in Biomedicine 157:95–111, 2018
Wang N, Yeung DY: Learning a deep compact image representation for visual tracking. In Advances in Neural Information Processing Systems:809–817, 2013
Gao J, Ling H, Hu W, and Xing J. Transfer learning based visual tracking with gaussian processes regression. In ECCV. 188–203. (2014).
Liu Y, Sui X, Kuang X, Liu C, Gu G, Chen Q: Object Tracking Based on Vector Convolutional Network and Discriminant Correlation Filters. Sensors 19(8):2019, 1818
Irshad M, Muhammad N, Sharif M, Yasmeen M: Automatic segmentation of the left ventricle in a cardiac MR short axis image using blind morphological operation. The European Physical Journal Plus 133(4):148, 2018
Kim K, Lee S: Vertebrae localization in CT using both local and global symmetry features. Comput Med Imaging Graph 58:45–55, 2017
Han Z, Wei B, Leung S et al.: Automated Pathogenesis-Based Diagnosis of Lumbar Neural Foraminal Stenosis via Deep Multiscale Multitask Learning. Neuro informatics 1:1–13, 2018
Wang J, Fang Z, Lang N, Yuan H, Su MY, Baldi P: A multi-resolution approach for spinal metastasis detection using deep Siamese neural networks. Computers in Biology & Medicine 84(C):137–146, 2017
Forsberg D, Sjöblom E, Sunshine JL: Detection and Labeling of Vertebrae in MR Images Using Deep Learning with Clinical Annotations as Training Data. Journal of Digital Imaging 30(4):1–7, 2017
Krizhevsky A, Sutskever I, Hinton GE: ImageNet classification with deep convolutional neural networks. International Conference on Neural Information Processing Systems. Curran Associates Inc 60(2):1097–1105, 2012
Girshick R, Donahue J, Darrell T and Malik J. Rich feature hierarchies for accurate object detection and semantic segmentation. In CVPR, (2014).
Russakovsky O, Deng J, Su H, Krause J, Satheesh S, Ma S, Huang Z, Karpathy A, Khosla A, Bernstein M, Berg A C, Fei-Fei L. ImageNet Large Scale Visual Recognition Challenge. IJCV (2015).
Oktay AB, Akgul YS: Simultaneous Localization of Lumbar Vertebrae and Intervertebral Discs With SVM-Based MRF. IEEE Trans Biomed Eng 60(9):2375–2383, 2013
Vedaldi, A. and Lenc, K., “Matconvnet: Convolutional neural networks for matlab,” Proc. ACM International Conference on Multimedia, (2015).
Acknowledgments
This research was financially supported by National Natural Science Foundation of China, (grant number 11503010, 11773018), the Fundamental Research Funds for the Central Universities, (grant number 30916015103), and Qing Lan Project and Open Research Fund of Jiangsu Key Laboratory of Spectral Imaging & Intelligence Sense (3091601410405).
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Liu, Y., Sui, X., Liu, C. et al. Automatic Lumbar Spine Tracking Based on Siamese Convolutional Network. J Digit Imaging 33, 423–430 (2020). https://doi.org/10.1007/s10278-019-00273-5
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10278-019-00273-5