Abstract
The circadian rhythm controls the unconscious activities of living beings through the biological clock. External influences, such as pain, migraine, depression or anxiety, cause dysfunction in the synchronization and desynchronization of the human body. We propose to study the mathematical and computational properties that can describe the modeling of circadian rhythm, specifically with the influence of pain. We use a mathematical model of two processes, composed of circadian and homeostatic rhythms. The computational model, via a multiagent system, will use the pain variable, that will define by a non-invasive questionnaire with people. Preliminary results show that pain directly influences the quality of sleep, as well as the development of daily activities.
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References
International association for the study pain. https://www.iasp-pain.org/. Accessed 22 Oct 2017
Asgari-Targhi, A., Klerman, E.B.: Mathematical modeling of circadian rhythms. Wiley Interdisc. Rev. Syst. Biol. Med. 11(2), e1439 (2019)
Borbély, A.A., Daan, S., Wirz-Justice, A., Deboer, T.: The two-process model of sleep regulation: a reappraisal. J. Sleep Res. 25(2), 131–143 (2016)
Daan, S., Beersma, D., Borbély, A.A.: Timing of human sleep: recovery process gated by a circadian pacemaker. Am. J. Physiol. Regul. Integr. Comp. Physiol. 246(2), R161–R183 (1984)
Li, Z., Duan, Z.: Cooperative Control of Multi-agent Systems: A Consensus Region Approach. CRC Press, Boca Raton (2017)
Skeldon, A.: Are you listening to your body clock? http://personal.maths.surrey.ac.uk/st/A.Skeldon/sleep.html (2014). Accessed 20 Feb 2020
Turk, D.C., Monarch, E.S.: Biopsychosocial perspective on chronic pain. In: Turk, D.C., Gatchel, R.J. (eds.) Psychological Approaches to Pain Management: A Practitioner‘s Handbook, pp. 3–29. The Guilford Press (2002)
Zaki, N.F., Spence, D.W., BaHammam, A.S., Pandi-Perumal, S.R., Cardinali, D.P., Brown, G.M.: Chronobiological theories of mood disorder. Eur. Arch. Psychiatry Clin. Neurosci. 268(2), 107–118 (2018)
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dos Santos, A.T., dos Santos Machado, C.M., Adamatti, D.F. (2021). Circadian Rhythm and Pain: Mathematical Model Based on Multiagent Simulation. In: Novais, P., Vercelli, G., Larriba-Pey, J.L., Herrera, F., Chamoso, P. (eds) Ambient Intelligence – Software and Applications. ISAmI 2020. Advances in Intelligent Systems and Computing, vol 1239. Springer, Cham. https://doi.org/10.1007/978-3-030-58356-9_37
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DOI: https://doi.org/10.1007/978-3-030-58356-9_37
Publisher Name: Springer, Cham
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