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Artificial Immune System for Classification of Cancer

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Applications of Evolutionary Computing (EvoWorkshops 2003)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2611))

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Abstract

This paper presents a method for cancer type classification based on microarray-monitored data. The method is based on artificial immune system(AIS), which utilizes immunological recognition for classification. The system evolutionarily selects important genes; optimize their weights to derive classification rules. This system was applied to gene expression data of acute leukemia patients to classify their cancer class. The primary result found few classification rules which correctly classified all the test samples and gave some interesting implications for feature selection principles.

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Author information

Authors and Affiliations

  1. Dept. of Electronics Engineering, School of Engineering University of Tokyo, Japan

    Shin Ando

  2. Dept. of Frontier Informatics, School of Frontier Science, University of Tokyo, Japan

    Hitoshi Iba

Authors
  1. Shin Ando
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  2. Hitoshi Iba
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Editor information

Editors and Affiliations

  1. Dept. of Computer Engineering, University of Parma, Parco Area delle Scienze 181/a, 43100, Parma, Italy

    Stefano Cagnoni

  2. Computing Laboratory, University of Kent, Canterbury, Kent, CT2 7NF, UK

    Colin G. Johnson

  3. Dept. of Information and Communications Technologies Faculty of Computer Science, University of A Coruña, A Coruña, CP 15071, Spain

    Juan J. Romero Cardalda

  4. Dept. of Mathematics and Computer Science, Free University of Amsterdam, de Boelelaan 1081a, 1081 HV, Amsterdam, The Netherlands

    Elena Marchiori

  5. Schol of Systems Engineering, University of Reading, PO Box 225, Whiteknights, Reading, RG6 6AY, UK

    David W. Corne

  6. AnimatLab, 8 rue du capitaine Scott, 75015, Paris, France

    Jean-Arcady Meyer  & Agnès Guillot  & 

  7. SAP AG, Neurottstrasse 16, 69190, Walldorf, Germany

    Jens Gottlieb

  8. Parallel Computing and Complex Systems Group, University of Leipzig, Augustusplatz 10/11, 04109, Leipzig, Germany

    Martin Middendorf

  9. Algorithms and Data Structures Group Institute of Computer Graphics, Vienna University of Technology, Favoritenstrasse 9-11/186, 1040, Vienna, Austria

    Günther R. Raidl

  10. School of Computing, Napier University, 219 Colinton Road, Edinburgh, EH14 1DJ, UK

    Emma Hart

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© 2003 Springer-Verlag Berlin Heidelberg

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Ando, S., Iba, H. (2003). Artificial Immune System for Classification of Cancer. In: Cagnoni, S., et al. Applications of Evolutionary Computing. EvoWorkshops 2003. Lecture Notes in Computer Science, vol 2611. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-36605-9_1

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  • DOI: https://doi.org/10.1007/3-540-36605-9_1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00976-4

  • Online ISBN: 978-3-540-36605-8

  • eBook Packages: Springer Book Archive

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